diff --git a/packages/nuxt/src/app/components/nuxt-root.vue b/packages/nuxt/src/app/components/nuxt-root.vue
index 80a9d38ac1..378c8ee59c 100644
--- a/packages/nuxt/src/app/components/nuxt-root.vue
+++ b/packages/nuxt/src/app/components/nuxt-root.vue
@@ -24,7 +24,7 @@ const nuxtApp = useNuxtApp()
 const onResolve = nuxtApp.deferHydration()
 
 const url = import.meta.server ? nuxtApp.ssrContext.url : window.location.pathname
-const SingleRenderer = import.meta.test && import.meta.dev && import.meta.server && url.startsWith('/__nuxt_component_test__/') && /* #__PURE__ */ defineAsyncComponent(() => import('#build/test-component-wrapper.mjs')
+const SingleRenderer = import.meta.test && import.meta.dev && import.meta.server && url.startsWith('/__nuxt_component_test__/') && defineAsyncComponent(() => import('#build/test-component-wrapper.mjs')
   .then(r => r.default(import.meta.server ? url : window.location.href)))
 
 // Inject default route (outside of pages) as active route
diff --git a/packages/nuxt/src/components/loader.ts b/packages/nuxt/src/components/loader.ts
index 5e42223bb3..d219705462 100644
--- a/packages/nuxt/src/components/loader.ts
+++ b/packages/nuxt/src/components/loader.ts
@@ -74,12 +74,12 @@ export const loaderPlugin = createUnplugin((options: LoaderOptions) => {
           if (lazy) {
             imports.add(genImport('vue', [{ name: 'defineAsyncComponent', as: '__defineAsyncComponent' }]))
             identifier += '_lazy'
-            imports.add(`const ${identifier} = /*#__PURE__*/ __defineAsyncComponent(${genDynamicImport(component.filePath, { interopDefault: true })}${isClientOnly ? '.then(c => createClientOnly(c))' : ''})`)
+            imports.add(`const ${identifier} = __defineAsyncComponent(${genDynamicImport(component.filePath, { interopDefault: true })}${isClientOnly ? '.then(c => createClientOnly(c))' : ''})`)
           } else {
             imports.add(genImport(component.filePath, [{ name: component.export, as: identifier }]))
 
             if (isClientOnly) {
-              imports.add(`const ${identifier}_wrapped = /*#__PURE__*/ createClientOnly(${identifier})`)
+              imports.add(`const ${identifier}_wrapped = createClientOnly(${identifier})`)
               identifier += '_wrapped'
             }
           }
diff --git a/packages/nuxt/src/components/runtime/server-component.ts b/packages/nuxt/src/components/runtime/server-component.ts
index b8d7e216a3..e1f75e6a59 100644
--- a/packages/nuxt/src/components/runtime/server-component.ts
+++ b/packages/nuxt/src/components/runtime/server-component.ts
@@ -1,6 +1,7 @@
 import { defineComponent, h } from 'vue'
 import NuxtIsland from '#app/components/nuxt-island'
 
+/*! @__NO_SIDE_EFFECTS__ */
 export const createServerComponent = (name: string) => {
   return defineComponent({
     name,
diff --git a/packages/nuxt/src/components/templates.ts b/packages/nuxt/src/components/templates.ts
index 2847270a33..d0e250c5a7 100644
--- a/packages/nuxt/src/components/templates.ts
+++ b/packages/nuxt/src/components/templates.ts
@@ -90,7 +90,7 @@ export const componentsIslandsTemplate: NuxtTemplate<ComponentsTemplateContext>
       (c) => {
         const exp = c.export === 'default' ? 'c.default || c' : `c['${c.export}']`
         const comment = createImportMagicComments(c)
-        return `export const ${c.pascalName} = /* #__PURE__ */ defineAsyncComponent(${genDynamicImport(c.filePath, { comment })}.then(c => ${exp}))`
+        return `export const ${c.pascalName} = defineAsyncComponent(${genDynamicImport(c.filePath, { comment })}.then(c => ${exp}))`
       }
     )].join('\n')
   }
diff --git a/packages/nuxt/src/pages/runtime/composables.ts b/packages/nuxt/src/pages/runtime/composables.ts
index 24714cd252..3b1ee9210c 100644
--- a/packages/nuxt/src/pages/runtime/composables.ts
+++ b/packages/nuxt/src/pages/runtime/composables.ts
@@ -76,5 +76,6 @@ export const definePageMeta = (meta: PageMeta): void => {
  * For more control, such as if you are using a custom `path` or `alias` set in the page's `definePageMeta`, you
  * should set `routeRules` directly within your `nuxt.config`.
  */
+/*! @__NO_SIDE_EFFECTS__ */
 // eslint-disable-next-line @typescript-eslint/no-unused-vars
 export const defineRouteRules = (rules: NitroRouteConfig): void => {}
diff --git a/packages/vite/src/client.ts b/packages/vite/src/client.ts
index a8dca717fa..171f314cff 100644
--- a/packages/vite/src/client.ts
+++ b/packages/vite/src/client.ts
@@ -15,7 +15,6 @@ import type { ViteBuildContext } from './vite'
 import { devStyleSSRPlugin } from './plugins/dev-ssr-css'
 import { runtimePathsPlugin } from './plugins/paths'
 import { typeCheckPlugin } from './plugins/type-check'
-import { pureAnnotationsPlugin } from './plugins/pure-annotations'
 import { viteNodePlugin } from './vite-node'
 import { createViteLogger } from './utils/logger'
 
@@ -80,11 +79,7 @@ export async function buildClient (ctx: ViteBuildContext) {
       runtimePathsPlugin({
         sourcemap: !!ctx.nuxt.options.sourcemap.client
       }),
-      viteNodePlugin(ctx),
-      pureAnnotationsPlugin.vite({
-        sourcemap: !!ctx.nuxt.options.sourcemap.client,
-        functions: ['defineComponent', 'defineAsyncComponent', 'defineNuxtLink', 'createClientOnly', 'defineNuxtPlugin', 'defineNuxtRouteMiddleware', 'defineNuxtComponent', 'useRuntimeConfig', 'defineRouteRules']
-      })
+      viteNodePlugin(ctx)
     ],
     appType: 'custom',
     server: {
diff --git a/packages/vite/src/plugins/pure-annotations.ts b/packages/vite/src/plugins/pure-annotations.ts
deleted file mode 100644
index 9154f54863..0000000000
--- a/packages/vite/src/plugins/pure-annotations.ts
+++ /dev/null
@@ -1,40 +0,0 @@
-import MagicString from 'magic-string'
-import { createUnplugin } from 'unplugin'
-import { stripLiteral } from 'strip-literal'
-import { isJS, isVue } from '../../../nuxt/src/core/utils/plugins'
-
-interface PureAnnotationsOptions {
-  sourcemap: boolean
-  functions: string[]
-}
-
-export const pureAnnotationsPlugin = createUnplugin((options: PureAnnotationsOptions) => {
-  const FUNCTION_RE = new RegExp(`(?<!\\/\\* #__PURE__ \\*\\/ )\\b(${options.functions.join('|')})\\s*\\(`, 'g')
-  const FUNCTION_RE_SINGLE = new RegExp(`(?<!\\/\\* #__PURE__ \\*\\/ )\\b(${options.functions.join('|')})\\s*\\(`)
-  return {
-    name: 'nuxt:pure-annotations',
-    enforce: 'post',
-    transformInclude (id) {
-      return isVue(id, { type: ['script'] }) || isJS(id)
-    },
-    transform (code) {
-      if (!FUNCTION_RE_SINGLE.test(code)) { return }
-
-      const s = new MagicString(code)
-      const strippedCode = stripLiteral(code)
-
-      for (const match of strippedCode.matchAll(FUNCTION_RE)) {
-        s.overwrite(match.index!, match.index! + match[0].length, '/* #__PURE__ */ ' + match[0])
-      }
-
-      if (s.hasChanged()) {
-        return {
-          code: s.toString(),
-          map: options.sourcemap
-            ? s.generateMap({ hires: true })
-            : undefined
-        }
-      }
-    }
-  }
-})
diff --git a/packages/vite/src/server.ts b/packages/vite/src/server.ts
index 3a3117b15e..7bc3be4822 100644
--- a/packages/vite/src/server.ts
+++ b/packages/vite/src/server.ts
@@ -8,7 +8,6 @@ import type { ViteConfig } from '@nuxt/schema'
 import type { ViteBuildContext } from './vite'
 import { createViteLogger } from './utils/logger'
 import { initViteNodeServer } from './vite-node'
-import { pureAnnotationsPlugin } from './plugins/pure-annotations'
 import { writeManifest } from './manifest'
 import { transpile } from './utils/transpile'
 
@@ -101,12 +100,7 @@ export async function buildServer (ctx: ViteBuildContext) {
       preTransformRequests: false,
       hmr: false
     },
-    plugins: [
-      pureAnnotationsPlugin.vite({
-        sourcemap: !!ctx.nuxt.options.sourcemap.server,
-        functions: ['defineComponent', 'defineAsyncComponent', 'defineNuxtLink', 'createClientOnly', 'defineNuxtPlugin', 'defineNuxtRouteMiddleware', 'defineNuxtComponent', 'useRuntimeConfig', 'defineRouteRules']
-      })
-    ]
+    plugins: []
   } satisfies vite.InlineConfig, ctx.nuxt.options.vite.$server || {}))
 
   if (!ctx.nuxt.options.dev) {