diff --git a/include/pybind11/pytypes.h b/include/pybind11/pytypes.h
index a837fb9fa..6ba1f5f20 100644
--- a/include/pybind11/pytypes.h
+++ b/include/pybind11/pytypes.h
@@ -2420,6 +2420,7 @@ PYBIND11_MATH_OPERATOR_BINARY_INPLACE(operator>>=, PyNumber_InPlaceRshift)
 
 #undef PYBIND11_MATH_OPERATOR_UNARY
 #undef PYBIND11_MATH_OPERATOR_BINARY
+#undef PYBIND11_MATH_OPERATOR_BINARY_INPLACE
 
 PYBIND11_NAMESPACE_END(detail)
 PYBIND11_NAMESPACE_END(PYBIND11_NAMESPACE)